Drug Information

Drug General Information
Drug ID
D0T0NG
Former ID
DCL000700
Drug Name
Arofylline
Synonyms
Arofyllin; KM09088; Arofylline (USAN/INN); 3-(4-chlorophenyl)-1-propyl-3,7-dihydro-1H-purine-2,6-dione; 3-(4-chlorophenyl)-1-propyl-7H-purine-2,6-dione
Drug Type
Small molecular drug
Indication Chronic obstructive pulmonary disease [ICD9: 490-492, 494-496; ICD10:J40-J44, J47] Phase 3 [536223]
Company
Almiral Prodesfarma
Structure
Download
2D MOL

3D MOL
Formula
C14H13ClN4O2
Canonical SMILES
CCCN1C(=O)C2=C(N=CN2)N(C1=O)C3=CC=C(C=C3)Cl
InChI
1S/C14H13ClN4O2/c1-2-7-18-13(20)11-12(17-8-16-11)19(14(18)21)10-5-3-9(15)4-6-10/h3-6,8H,2,7H2,1H3,(H,16,17)
InChIKey
GVTLDPJNRVMCAL-UHFFFAOYSA-N
CAS Number
CAS 136145-07-8
PubChem Compound ID
166553
PubChem Substance ID
3283044, 6882030, 10256121, 14776327, 14874003, 17397141, 26730391, 46240221, 57350927, 58754695, 77030132, 89758911, 103010060, 103123726, 113458554, 117469418, 124953018, 125144922, 125517596, 128013468, 134339204, 135121134, 137033002, 137242633, 140137137, 160677236, 162309999, 162788494, 179149859, 179417132, 198937617, 224080652, 226491163
Target and Pathway
Target(s) PDE4 Target Info Inhibitor [536223]
References
Ref 536223Emerging drugs for the treatment of chronic obstructive pulmonary disease. Expert Opin Emerg Drugs. 2006 May;11(2):275-91.
Ref 536223Emerging drugs for the treatment of chronic obstructive pulmonary disease. Expert Opin Emerg Drugs. 2006 May;11(2):275-91.

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