Drug General Information
Drug ID
D0V0BO
Former ID
DCL001144
Drug Name
Anti-FGFR3
Drug Type
Antibody
Indication Multiple myeloma [ICD9: 203; ICD10:C90] Phase 1 [550794]
Company
Genentech
Target and Pathway
Target(s) FGF-3 receptor Target Info [550794]
KEGG Pathway MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
Endocytosis
PI3K-Akt signaling pathway
Signaling pathways regulating pluripotency of stem cells
Regulation of actin cytoskeleton
Pathways in cancer
MicroRNAs in cancer
Bladder cancer
Central carbon metabolism in cancer
PANTHER Pathway FGF signaling pathway
Reactome FGFR3 mutant receptor activation
WikiPathways Regulation of Actin Cytoskeleton
Endochondral Ossification
Bladder Cancer
Neural Crest Differentiation
Signaling by FGFR
References
Ref 550794Clinical pipeline report, company report or official report of Genentech (2011).
Ref 550794Clinical pipeline report, company report or official report of Genentech (2011).

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