Drug Information
Drug General Information | |||||
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Drug ID |
D0V0CJ
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Former ID |
DNCL002647
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Drug Name |
CO-101
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Drug Type |
Small molecular drug
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Indication | Metastatic pancreatic [ICD10:C25.9] | Phase 2 | [523237] | ||
Company |
Clovis Oncology
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Structure |
Download2D MOL |
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Formula |
C11H13NO3
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Canonical SMILES |
CN(C)C(=O)C1=CC=CC=C1C(=O)OC
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InChI |
1S/C11H13NO3/c1-12(2)10(13)8-6-4-5-7-9(8)11(14)15-3/h4-7H,1-3H3
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InChIKey |
HJPZFXYWMRWNHV-UHFFFAOYSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Human DNA | Target Info | Inhibitor | [528281] | |
Ribonucleoside-diphosphatereductase subunit M2 | Target Info | Inhibitor | [528281] | ||
BioCyc Pathway | Pyrimidine deoxyribonucleotides biosynthesis from CTP | ||||
Pyrimidine deoxyribonucleotides de novo biosynthesis | |||||
Guanosine nucleotides de novo biosynthesis | |||||
Superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis | |||||
Superpathway of purine nucleotide salvage | |||||
Purine nucleotides de novo biosynthesis | |||||
Adenosine deoxyribonucleotides de novo biosynthesis | |||||
Guanosine deoxyribonucleotides de novo biosynthesis | |||||
NetPath Pathway | EGFR1 Signaling Pathway | ||||
Pathway Interaction Database | E2F transcription factor network | ||||
PathWhiz Pathway | Purine Metabolism | ||||
Pyrimidine Metabolism | |||||
References |
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