TTD | Drug: D0X5AY

Drug General Information
Drug ID	D0X5AY
Former ID	DNC007419
Drug Name	1-(4-methoxyphenyl)-3-(5-methylthiazol-2-yl)urea
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[528805]
Structure		Download 2D MOL 3D MOL
Formula	C12H13N3O2S
Canonical SMILES	CC1=CN=C(S1)NC(=O)NC2=CC=C(C=C2)OC
InChI	1S/C12H13N3O2S/c1-8-7-13-12(18-8)15-11(16)14-9-3-5-10(17-2)6-4-9/h3-7H,1-2H3,(H2,13,14,15,16)
InChIKey	OHPUNXDCCJNSEH-UHFFFAOYSA-N
PubChem Compound ID	771042
Target and Pathway
Target(s)	mRNA of human 5-lipoxygenase	Target Info	Inhibitor	[528805]
BioCyc Pathway	Aspirin-triggered lipoxin biosynthesis
	Resolvin D biosynthesis
	Leukotriene biosynthesis
	Lipoxin biosynthesis
	Aspirin triggered resolvin D biosynthesis
	Aspirin triggered resolvin E biosynthesis
KEGG Pathway	Arachidonic acid metabolism
	Metabolic pathways
	Serotonergic synapse
	Ovarian steroidogenesis
	Toxoplasmosis
NetPath Pathway	IL4 Signaling Pathway
PathWhiz Pathway	Arachidonic Acid Metabolism
WikiPathways	Arachidonic acid metabolism
	Eicosanoid Synthesis
	Selenium Micronutrient Network
References
Ref 528805	J Med Chem. 2007 May 31;50(11):2640-6. Epub 2007 Apr 27.Identification of natural-product-derived inhibitors of 5-lipoxygenase activity by ligand-based virtual screening.
Ref 528805	J Med Chem. 2007 May 31;50(11):2640-6. Epub 2007 Apr 27.Identification of natural-product-derived inhibitors of 5-lipoxygenase activity by ligand-based virtual screening.

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Drug Information