Drug General Information
Drug ID
D0X8TP
Former ID
DNC001384
Drug Name
SU10991
Drug Type
Small molecular drug
Indication Multiple myeloma [ICD9: 203; ICD10:C90] Investigative [537114]
Company
Sugen Inc
Structure
Download
2D MOL

3D MOL

Formula
C10H15N5
Canonical SMILES
CCN(CC)C1=CC(=NC2=NC=NN12)C
InChI
1S/C10H15N5/c1-4-14(5-2)9-6-8(3)13-10-11-7-12-15(9)10/h6-7H,4-5H2,1-3H3
InChIKey
GSNOZLZNQMLSKJ-UHFFFAOYSA-N
PubChem Compound ID
PubChem Substance ID
SuperDrug ATC ID
C01DX11
SuperDrug CAS ID
cas=015421848
Target and Pathway
Target(s) FGF-3 receptor Target Info Inhibitor [537114]
KEGG Pathway MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
Endocytosis
PI3K-Akt signaling pathway
Signaling pathways regulating pluripotency of stem cells
Regulation of actin cytoskeleton
Pathways in cancer
MicroRNAs in cancer
Bladder cancer
Central carbon metabolism in cancer
PANTHER Pathway FGF signaling pathway
Reactome FGFR3 mutant receptor activation
WikiPathways Regulation of Actin Cytoskeleton
Endochondral Ossification
Bladder Cancer
Neural Crest Differentiation
Signaling by FGFR
References
Ref 537114Emerging therapies for multiple myeloma. Expert Opin Emerg Drugs. 2009 Mar;14(1):99-127.
Ref 537114Emerging therapies for multiple myeloma. Expert Opin Emerg Drugs. 2009 Mar;14(1):99-127.

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