Drug Information

Drug General Information
Drug ID
D0Y5DO
Former ID
DAP000118
Drug Name
Citalopram
Synonyms
Akarin; Celapram; Celexa; Celius; Ciazil; Cilift; Cipram; Ciprapine; Citabax; Citadur; Citalec; Citalopramum; Citopam; Cytalopram; Dalsan; Humorup; Nitalapram; Oropram; Pramcit; Recital; Seropram; Talam; Talohexal; Temperax; Vodelax; Zentius; Zetalo; Citalopram [Celexa]; [3H]Citalopram; Akarin (TN); Celapram (TN); Celexa (TN); Celius (TN); Ciazil (TN); Cilift (TN); Cipram (TN); Cipramil (TN); Ciprapine (TN); Citabax (TN); Citadur (TN); Citalec (TN); Citalopram [INN:BAN]; Citalopramum [INN-Latin]; Citaxin (TN); Citol (TN); Citopam (TN); Citox (TN); Citrol (TN); Dalsan (TN); Lu 10-171; Recital (TN); Seropram (TN); Talam (TN); Zentius (TN); Zetalo (TN); AE-641/00603021; Citalopram (USP/INN); Lu-10-171; 1,3-Dihydro-1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-5-isobenzofurancarbonitrile; 1,3-dihydro[3,4]benzofuran-5-carbonitrile; 1-(3-(Dimethylamino)propyl)-1-(p-fluorophenyl)-5-phthalancarbonitrile; 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile; 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-3H-2-benzofuran-5-carbonitrile
Drug Type
Small molecular drug
Indication Depression [ICD9: 311; ICD10:F30-F39] Approved [536306], [542548]
Therapeutic Class
Antidepressants
Company
Forest Laboratories, Inc
Structure
Download
2D MOL

3D MOL
Formula
C20H21FN2O
InChI
InChI=1S/C20H21FN2O/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24-20/h4-9,12H,3,10-11,14H2,1-2H3
InChIKey
WSEQXVZVJXJVFP-UHFFFAOYSA-N
CAS Number
CAS 59729-33-8
PubChem Compound ID
2771
PubChem Substance ID
9775, 855965, 4445124, 7978955, 8151789, 14826333, 24723457, 29221926, 46508746, 47656601, 47730750, 47879631, 48253450, 48415786, 48493834, 49699144, 49985355, 50104852, 51092001, 53788845, 56313600, 56413158, 57321451, 80123691, 80953770, 85209895, 85787315, 87690083, 90340852, 92307844, 92309285, 92711474, 99418031, 103177051, 104170209, 104301562, 121362384, 124570949, 124749575, 124879738, 124879739, 125353996, 126440716, 126525331, 126630818, 126657311, 126666544, 127275913, 127275914, 127275915
ChEBI ID
ChEBI:3723
SuperDrug ATC ID
N06AB04
SuperDrug CAS ID
cas=059729338
Target and Pathway
Target(s) Sodium-dependent serotonin transporter Target Info Modulator [556264]
KEGG Pathway Serotonergic synapse
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway 5HT1 type receptor mediated signaling pathway
5HT2 type receptor mediated signaling pathway
5HT3 type receptor mediated signaling pathway
5HT4 type receptor mediated signaling pathway
WikiPathways Monoamine Transport
SIDS Susceptibility Pathways
NRF2 pathway
Synaptic Vesicle Pathway
Serotonin Transporter Activity
References
Ref 536306Emerging treatments for depression. Expert Opin Pharmacother. 2006 Dec;7(17):2323-39.
Ref 542548(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7547).
Ref 556264Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.

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