Drug Information

Drug General Information
Drug ID
D0ZB7Z
Former ID
DIB021231
Drug Name
XCT790
Synonyms
XCT 790; XCT-790
Drug Type
Small molecular drug
Indication Discovery agent Investigative [539874]
Structure
Download
2D MOL
Formula
C23H13F9N4O3S
InChI
InChI=1S/C23H13F9N4O3S/c1-38-17-7-11(6-13(9-33)18(37)34-20-36-35-19(40-20)23(30,31)32)2-5-16(17)39-10-12-3-4-14(21(24,25)26)8-15(12)22(27,28)29/h2-8H,10H2,1H3,(H,34,36,37)/b13-6+
InChIKey
HQFNFOOGGLSBBT-AWNIVKPZSA-N
PubChem Compound ID
6918788
PubChem Substance ID
12015852, 15013052, 17195093, 17396631, 24724669, 29217710, 43530151, 47288892, 53788748, 57372023, 74959514, 85844594, 90341312, 103456869, 104043200, 114788553, 121362032, 135277320, 135651333, 162248128, 163565217, 172919889, 175426335, 175612761, 204356778, 210274684, 210280317, 223400858, 223445168, 241376711, 242060102, 249618023, 252157643, 252160933, 252554221
Target and Pathway
Target(s) Steroid hormone receptor ERR1 Target Info Antagonist [535978]
Reactome PPARA activates gene expression
Transcriptional activation of mitochondrial biogenesis
Nuclear Receptor transcription pathway
WikiPathways Mitochondrial Gene Expression
Regulation of Lipid Metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Nuclear Receptors
References
Ref 539874(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2832).
Ref 535978Regulation of PPARgamma coactivator 1alpha (PGC-1alpha) signaling by an estrogen-related receptor alpha (ERRalpha) ligand. Proc Natl Acad Sci U S A. 2004 Jun 15;101(24):8912-7. Epub 2004 Jun 7.

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