| Target Validation Information | |||||
|---|---|---|---|---|---|
| Target ID | T88452 | ||||
| Target Name | Corticosteroid-binding globulin | ||||
| Target Type | Successful |
||||
| Drug Potency against Target | Ciclesonide | Drug Info | IC50 = 210 nM | [552519] | |
| Action against Disease Model | Triamcinolone | Type II corticosterold receptors measured in whole C6 glioma cells IC50: 2.5 nM | Drug Info | ||
| References | |||||
| Ref 552519 | Preclinical profile of ciclesonide, a novel corticosteroid for the treatment of asthma. J Pharmacol Exp Ther. 2005 Aug;314(2):568-74. Epub 2005 May 5. | ||||
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