| Target Validation Information | |||||
|---|---|---|---|---|---|
| Target ID | T30563 | ||||
| Target Name | Leukotriene B4 receptor 2 | ||||
| Target Type | Discontinued |
||||
| Drug Potency against Target | SC-41390 | Drug Info | IC50 = 200 nM | ||
| CP-105696 | Drug Info | IC50 = 5 nM | |||
| LY-292728 | Drug Info | IC50 = 1.2 nM | [533960] | ||
| LEUKOTRIENE_B4 | Drug Info | IC50 = 1.9 nM | |||
| LY-282210 | Drug Info | IC50 = 47 nM | [533960] | ||
| (3S,4R)-3-Benzyl-7-isopropyl-chroman-4-ol | Drug Info | IC50 = 7200 nM | |||
| References | |||||
| Ref 533960 | J Med Chem. 1993 Nov 26;36(24):3982-4.Biphenylyl-substituted xanthones: highly potent leukotriene B4 receptor antagonists. | ||||
| Ref 533960 | J Med Chem. 1993 Nov 26;36(24):3982-4.Biphenylyl-substituted xanthones: highly potent leukotriene B4 receptor antagonists. | ||||
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