| Target Validation Information | |||||
|---|---|---|---|---|---|
| Target ID | T86273 | ||||
| Target Name | TGR5 | ||||
| Target Type | Clinical Trial |
||||
| Drug Potency against Target | Bile acid | Drug Info | IC50 = 140 nM | [531132] | |
| References | |||||
| Ref 531132 | Bioorg Med Chem Lett. 2010 Oct 1;20(19):5718-21. Epub 2010 Aug 10.Synthesis and SAR of 2-aryl-3-aminomethylquinolines as agonists of the bile acid receptor TGR5. | ||||
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