Biomarker General Infomation
Biomarker ID
BM003140
Biomarker Name
Envelope glycoprotein complex
Disease Human immunodeficiency virus infection
ICD Code ICD-11: 1C62 ; ICD-10: B17.1, B18.2
Biomarker Type Pharmacodynamic
Specific Aim Pathogenesis
Conclusion The envelope glycoprotein complex (gp120/gp41)n of HIV-1 is one of the viral products responsible for increased apoptosis in HIV infection.
References
REF 1 The implication of the chemokine receptor CXCR4 in HIV-1 envelope protein-induced apoptosis is independent of the G protein-mediated signalling. AIDS. 1999 May 28;13(8):909-17. AIDS. 1999 May 28;13(8):909-17.

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