Biomarker General Infomation
Biomarker ID
BM003206
Biomarker Name
Stromal cell-derived factor 1 (CXCL12)
Disease Dengue
ICD Code ICD-11: 1D20-1D2Z ; ICD-10: A90, R50
Biomarker Type Differentiation
Biomarker Measure Increased
Conclusion HIV replication in dengue virus NS5-expressing cells decreased by >90% compared with control cells (P < .01), and this was mediated in part by decreased HIV coreceptor (CXCR4) expression and increased production of SDF-1.
UniProt ID
References
REF 1 Expression of the dengue virus type 2 NS5 protein in a CD4(+) T cell line inhibits HIV replication. J Infect Dis. 2008 Sep 15;198(6):860-3. J Infect Dis. 2008 Sep 15;198(6):860-3.

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