Biomarker General Infomation |
Biomarker ID |
BM003206 |
Biomarker Name |
Stromal cell-derived factor 1 (CXCL12) |
Disease |
Dengue |
ICD Code |
ICD-11: 1D20-1D2Z
; ICD-10: A90, R50
|
Biomarker Type |
Differentiation |
Biomarker Measure |
Increased |
Conclusion |
HIV replication in dengue virus NS5-expressing cells decreased by >90% compared with control cells (P < .01), and this was mediated in part by decreased HIV coreceptor (CXCR4) expression and increased production of SDF-1. |
UniProt ID |
|
References |
REF 1 |
Expression of the dengue virus type 2 NS5 protein in a CD4(+) T cell line inhibits HIV replication. J Infect Dis. 2008 Sep 15;198(6):860-3. J Infect Dis. 2008 Sep 15;198(6):860-3.
|
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