Biomarker General Infomation
Biomarker ID
BM003212
Biomarker Name
TNF related activation protein (CD40LG)
Disease Dengue
ICD Code ICD-11: 1D20-1D2Z ; ICD-10: A90, R50
Biomarker Type Monitoring
Specific Aim Disease severity
Conclusion The observation that CD40L signaling results in enhanced DV infection of DC suggests a possible T cell-dependent mechanism for the immune-mediated enhancement of disease severity associated with some secondary dengue infections.
UniProt ID
References
REF 1 CD40 ligand enhances dengue viral infection of dendritic cells: a possible mechanism for T cell-mediated immunopathology. J Immunol. 2006 Nov 1;177(9):6497-503. J Immunol. 2006 Nov 1;177(9):6497-503.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.