| Biomarker General Infomation |
| Biomarker ID |
BM003353 |
| Biomarker Name |
C-C chemokine receptor type 5 (CCR5) |
| Disease |
Human immunodeficiency virus infection |
| ICD Code |
ICD-11: 1C62
; ICD-10: B17.1, B18.2
|
| Biomarker Type |
Monitoring |
| Biomarker Measure |
Higher |
| Specific Aim |
Disease progression. |
| Conclusion |
The observation of a higher CCR5 co-receptor expression in HIV controllers suggests that HIV infection leads to the selection of CD4 cells with low CCR5 co-receptor density after HAART interruption. |
| UniProt ID |
|
| References |
| REF 1 |
Control of HIV-1 RNA load after HAART interruption: relationship with CCR5 co-receptor density and proviral DNA load in HIV-infected patients. J Clin Virol. 2007 Sep;40(1):64-7. J Clin Virol. 2007 Sep;40(1):64-7.
|
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