Biomarker General Infomation |
Biomarker ID |
BM003379 |
Biomarker Name |
Interleukin 7 receptor alpha (IL7R) |
Disease |
Human immunodeficiency virus infection |
ICD Code |
ICD-11: 1C62
; ICD-10: B17.1, B18.2
|
Biomarker Type |
Differentiation |
Biomarker Measure |
Lower |
Conclusion |
In HIV infection, decreased CD127 expression on T-cells is correlated with reduced CD4(+) T-cell counts, increased viral replication and immune activation. |
UniProt ID |
|
References |
REF 1 |
The influence of HIV on CD127 expression and its potential implications for IL-7 therapy. Semin Immunol. 2012 Jun;24(3):231-40. Semin Immunol. 2012 Jun;24(3):231-40.
|
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