Biomarker General Infomation
Biomarker ID
BM003379
Biomarker Name
Interleukin 7 receptor alpha (IL7R)
Disease Human immunodeficiency virus infection
ICD Code ICD-11: 1C62 ; ICD-10: B17.1, B18.2
Biomarker Type Differentiation
Biomarker Measure Lower
Conclusion In HIV infection, decreased CD127 expression on T-cells is correlated with reduced CD4(+) T-cell counts, increased viral replication and immune activation.
UniProt ID
References
REF 1 The influence of HIV on CD127 expression and its potential implications for IL-7 therapy. Semin Immunol. 2012 Jun;24(3):231-40. Semin Immunol. 2012 Jun;24(3):231-40.

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