Prodrug Information
| Prodrug General Information | Top | |||||
|---|---|---|---|---|---|---|
| Prodrug ID |
DI9XB6
|
|||||
| Prodrug Name |
PMID26729077-Compound-84
|
|||||
| Indication | Inflammation [ICD-11: 1A00-CA43.1] | Investigative | [1] | |||
| Activation |
Prodrug 
|
|
Parent Drug 
|
|||
| 2D MOL | 2D MOL | |||||
| Prodrug Strategy |
Classical prodrug strategy
[Carrier linked prodrug]
|
|||||
| Improved property |
Increase solubility
|
[1] | ||||
| Description |
The prodrug improved solubility from 1.6 microg/mL to 20.3 mg/mL.
|
[1] | ||||
| Parent Drug General Information | Top | |||||
|---|---|---|---|---|---|---|
| Parent Drug ID |
D7E2IF
|
|||||
| Parent Drug Name |
PC407
|
|||||
| References | Top | |||||
|---|---|---|---|---|---|---|
| REF 1 | Enhanced water-soluble derivative of PC407 as a novel potential COX-2 inhibitor injectable formulation. Bioorg Med Chem Lett. 2014 Oct 15;24(20):4794-7. | |||||
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