Drug Information
Drug General Information | |||||
---|---|---|---|---|---|
Drug ID |
DX2JYH
|
||||
Drug Name |
5-(3-(3,4-dihydroisoquinolin-2(1H)-yl)prop-1-ynyl)-4-(neopentylamino)pyrimidine-2-carbonitrile
|
||||
Synonyms |
CHEMBL261511
|
||||
Indication | Discovery agent | Investigative | [1587926] | ||
Formula |
C22H25N5
|
||||
Canonical SMILES |
CC(C)(C)CNc1nc(ncc1C#CCN2CCc3ccccc3C2)C#N
|
||||
InChI |
InChI=1S/C22H25N5/c1-22(2,3)16-25-21-18(14-24-20(13-23)26-21)9-6-11-27-12-10-17-7-4-5-8-19(17)15-27/h4-5,7-8,14H,10-12,15-16H2,1-3H3,(H,24,25,26)
|
||||
InChIKey |
NJKBASVLBVUNMW-UHFFFAOYSA-N
|
||||
Target and Pathway | |||||
Target(s) | Cathepsin K | Target Info | [1587926] | ||
Cathepsin L | Target Info | [1587926] | |||
Reactome | Collagen degradation | ||||
Degradation of the extracellular matrix | |||||
Activation of Matrix Metalloproteinases | |||||
Trafficking and processing of endosomal TLR | |||||
MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
Assembly of collagen fibrils and other multimeric structures | |||||
MHC class II antigen presentation | |||||
References |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.