Drug Information
Drug General Information | |||||
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Drug ID |
DX2PKA
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Drug Name |
(S)-3-cyclohexyl-1-morpholino-1-oxopropan-2-yl (S)-4-phenyl-1-(4-(trifluoromethoxy)phenylamino)butan-2-ylcarbamate
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Synonyms |
CHEMBL383968
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Indication | Discovery agent | Investigative | [1587926] | ||
Formula |
C31H40F3N3O5
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Canonical SMILES |
FC(F)(F)Oc1ccc(NC[C@H](CCc2ccccc2)NC(=O)O[C@@H](CC3CCCCC3)C(=O)N4CCOCC4)cc1
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InChI |
InChI=1S/C31H40F3N3O5/c32-31(33,34)42-27-15-13-25(14-16-27)35-22-26(12-11-23-7-3-1-4-8-23)36-30(39)41-28(21-24-9-5-2-6-10-24)29(38)37-17-19-40-20-18-37/h1,3-4,7-8,13-16,24,26,28,35H,2,5-6,9-12,17-22H2,(H,36,39)/t26-,28-/m0/s1
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InChIKey |
WHBDOPKKFKNZRI-XCZPVHLTSA-N
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Target and Pathway | |||||
Target(s) | Cathepsin K | Target Info | [1587926] | ||
Cathepsin L | Target Info | [1587926] | |||
Reactome | Collagen degradation | ||||
Degradation of the extracellular matrix | |||||
Activation of Matrix Metalloproteinases | |||||
Trafficking and processing of endosomal TLR | |||||
MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
Assembly of collagen fibrils and other multimeric structures | |||||
MHC class II antigen presentation | |||||
References |
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