Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXA9WK
|
||||
| Drug Name |
6-Cyclohexylamino-9-{2-[(2-methoxy-ethyl)-methyl-amino]-ethyl}-9H-purine-2-carbonitrile
|
||||
| Synonyms |
CHEMBL186062
|
||||
| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C18H27N7O
|
||||
| Canonical SMILES |
COCCN(C)CCn1cnc2c(NC3CCCCC3)nc(nc12)C#N
|
||||
| InChI |
InChI=1S/C18H27N7O/c1-24(10-11-26-2)8-9-25-13-20-16-17(21-14-6-4-3-5-7-14)22-15(12-19)23-18(16)25/h13-14H,3-11H2,1-2H3,(H,21,22,23)
|
||||
| InChIKey |
DEUHRFYIQWZXMJ-UHFFFAOYSA-N
|
||||
| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.