Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXF8ZT
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| Drug Name |
(R,S)-4-methyl-2-{3'-[2-(4-methyl-piperazin-1-yl)-thiazol-4-yl]-biphenyl-3-yl}-pentanoic acid cyanomethyl-amide
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| Synonyms |
CHEMBL213930
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C28H33N5OS
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| Canonical SMILES |
CC(C)CC(C(=O)NCC#N)c1cccc(c1)c2cccc(c2)c3csc(n3)N4CCN(C)CC4
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| InChI |
InChI=1S/C28H33N5OS/c1-20(2)16-25(27(34)30-11-10-29)23-8-4-6-21(17-23)22-7-5-9-24(18-22)26-19-35-28(31-26)33-14-12-32(3)13-15-33/h4-9,17-20,25H,11-16H2,1-3H3,(H,30,34)
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| InChIKey |
HLFQRRCBSFVYFQ-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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