Drug Information
Drug General Information | |||||
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Drug ID |
DXI1BN
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Drug Name |
N-((S)-4-cyclopentyl-1-((4S,7R)-7-methyl-3-oxo-1-(pyridin-2-ylsulfonyl)azepan-4-ylamino)-1-oxobutan-2-yl)furan-2-carboxamide
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Synonyms |
CHEMBL1807697
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Indication | Discovery agent | Investigative | [1587926] | ||
Formula |
C26H34N4O6S
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Canonical SMILES |
C[C@@H]1CC[C@H](NC(=O)[C@H](CCC2CCCC2)NC(=O)c3occc3)C(=O)CN1S(=O)(=O)c4ccccn4
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InChI |
InChI=1S/C26H34N4O6S/c1-18-11-13-20(22(31)17-30(18)37(34,35)24-10-4-5-15-27-24)28-25(32)21(14-12-19-7-2-3-8-19)29-26(33)23-9-6-16-36-23/h4-6,9-10,15-16,18-21H,2-3,7-8,11-14,17H2,1H3,(H,28,32)(H,29,33)/t18-,20+,21+/m1/s1
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InChIKey |
ROFMAUJRSYVSKK-GIVPXCGWSA-N
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Target and Pathway | |||||
Target(s) | Cathepsin K | Target Info | [1587926] | ||
Cathepsin L | Target Info | [1587926] | |||
Reactome | Collagen degradation | ||||
Degradation of the extracellular matrix | |||||
Activation of Matrix Metalloproteinases | |||||
Trafficking and processing of endosomal TLR | |||||
MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
Assembly of collagen fibrils and other multimeric structures | |||||
MHC class II antigen presentation | |||||
References |
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