Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXM4HH
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| Drug Name |
{(S)-1-[2-(4-Cyclopentyloxy-phenylamino)-ethylcarbamoyl]-3-methyl-butyl}-carbamic acid benzyl ester
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| Synonyms |
CHEMBL303517
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C27H37N3O4
|
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| Canonical SMILES |
CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)NCCNc2ccc(OC3CCCC3)cc2
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| InChI |
InChI=1S/C27H37N3O4/c1-20(2)18-25(30-27(32)33-19-21-8-4-3-5-9-21)26(31)29-17-16-28-22-12-14-24(15-13-22)34-23-10-6-7-11-23/h3-5,8-9,12-15,20,23,25,28H,6-7,10-11,16-19H2,1-2H3,(H,29,31)(H,30,32)/t25-/m0/s1
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| InChIKey |
SMXHVRTWHDVNLR-VWLOTQADSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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