Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXT0O6
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| Drug Name |
(4-Chloro-2-trifluoromethyl-phenyl)-carbamic acid 1-[(3-cyano-allylcarbamoyl)-methyl]-(3R)-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-ylmethyl ester
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| Synonyms |
CHEMBL504183
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C30H23ClF3N5O4
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| Canonical SMILES |
FC(F)(F)c1cc(Cl)ccc1NC(=O)OC[C@H]2N=C(c3ccccc3)c4ccccc4N(CC(=O)NC\\C=C\\C#N)C2=O
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| InChI |
InChI=1S/C30H23ClF3N5O4/c31-20-12-13-23(22(16-20)30(32,33)34)38-29(42)43-18-24-28(41)39(17-26(40)36-15-7-6-14-35)25-11-5-4-10-21(25)27(37-24)19-8-2-1-3-9-19/h1-13,16,24H,15,17-18H2,(H,36,40)(H,38,42)/b7-6+/t24-/m1/s1
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| InChIKey |
SHXKEOQRJUQIDC-DGQXCUQSSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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