Drug Information

Drug General Information
Drug ID
D00CFU
Former ID
DIB013057
Drug Name
RO-4840700
Synonyms
GlyT1 inhibitors (schizophrenia), Roche
Indication Schizophrenia [ICD9: 295; ICD10:F20] Investigative [543979]
Company
Roche Holding AG
Structure
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2D MOL

3D MOL
Canonical SMILES
C(=O)(N1Cc2c(C1)cc(cc2)C1CCOCC1)c1c(ccc(c1)S(=O)(=O)C)O<br />[C@H](C(F)(F)F)C
Target and Pathway
Target(s) Sodium- and chloride-dependent glycine transporter 1 Target Info Inhibitor [543979]
Reactome Na+/Cl- dependent neurotransmitter transporters
WikiPathways NRF2 pathway
References
Ref 543979(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 935).
Ref 543979(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 935).

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