Drug Information

Drug General Information
Drug ID
D00CTZ
Former ID
DNCL003384
Drug Name
MEDI9929
Indication Asthma [ICD10:J45] Phase 2 [524631]
Company
AstraZeneca
Target and Pathway
Target(s) Thymic stromal lymphopoietin Target Info Modulator [550624]
KEGG Pathway Cytokine-cytokine receptor interaction
Jak-STAT signaling pathway
WikiPathways TSLP Signaling Pathway
References
Ref 524631ClinicalTrials.gov (NCT02054130) Study to Evaluate the Efficacy and Safety of MEDI9929 (AMG 157) in Adult Subjects With Inadequately Controlled, Severe Asthma. U.S. National Institutes of Health.
Ref 550624Human immunoglobulin G2Lambda monoclonal antibody directed against thymic stromal lymphopoietin (MEDI9929). European medicines agency science medicines health (EMEA-001613-PIP01-14). European Union. 2015.

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