Drug Information

Drug General Information
Drug ID
D00JMY
Former ID
DNCL002219
Drug Name
AMP-224
Indication Solid tumours [ICD9: 140-199, 210-229; ICD10:C00-D48] Phase 1 [523471]
Company
Amplimmune Gaithersburg, MD
Target and Pathway
Target(s) PD-1 Target Info Modulator [550474]
KEGG Pathway Cell adhesion molecules (CAMs)
T cell receptor signaling pathway
Reactome PD-1 signaling
WikiPathways T-Cell Receptor and Co-stimulatory Signaling
Costimulation by the CD28 family
References
Ref 523471ClinicalTrials.gov (NCT01352884) Study to Assess the Safety, Tolerability, and Pharmacokinetics of AMP-224 in Patients With Advanced Cancer. U.S. National Institutes of Health.
Ref 550474National Cancer Institute Drug Dictionary (drug id 700595).

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