Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D00WUF
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| Former ID |
DIB013631
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| Drug Name |
Pregabalin
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| Synonyms |
Pregabalin CR; Pregabalin (controlled-release, oral); Pregabalin (controlled-release, oral), Pfizer
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| Drug Type |
Small molecular drug
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| Company |
Pfizer
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| Structure |
|
Download2D MOL |
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| Formula |
C8H17NO2
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| InChI |
InChI=1S/C8H17NO2/c1-6(2)3-7(5-9)4-8(10)11/h6-7H,3-5,9H2,1-2H3,(H,10,11)/t7-/m0/s1
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| InChIKey |
AYXYPKUFHZROOJ-ZETCQYMHSA-N
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| PubChem Compound ID | |||||
| PubChem Substance ID |
11694138, 12011767, 12014780, 15171006, 15219358, 17396883, 39472930, 46504934, 49831059, 49976228, 56365856, 57364178, 78321978, 92719096, 99431952, 103290097, 104050134, 104253343, 109692704, 113994486, 118046909, 118310941, 124772316, 126621090, 126659034, 126670344, 127479071, 131299586, 131403159, 134338500, 135081614, 135668336, 135684252, 136995650, 137006522, 142340821, 144205028, 160963578, 162111182, 163180654, 163621090, 163686413, 163801871, 164198004, 174006288, 175267702, 175612209, 178102131, 179149961, 184557778
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| Target and Pathway | |||||
| Target(s) | Voltage-dependent calcium channel subunit alpha-2/delta-1 | Target Info | Modulator | [528162] | |
| PANTHER Pathway | Muscarinic acetylcholine receptor 2 and 4 signaling pathway | ||||
| References | |||||
| Ref 528162 | Pregabalin reduces the release of synaptic vesicles from cultured hippocampal neurons. Mol Pharmacol. 2006 Aug;70(2):467-76. Epub 2006 Apr 26. | ||||
| Ref 540884 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5484). | ||||
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