Drug Information

Drug General Information
Drug ID
D01WKE
Former ID
DIB012772
Drug Name
Semapimod
Synonyms
CPSI-2364; Semapimod (oral); Semapimod (oral), Cytokine PharmaSciences
Drug Type
Small molecular drug
Indication Autoimmune diabetes [ICD10:E08-E13] Phase 2 [521518]
Company
Cytokine PharmaSciences Inc
Structure
Download
2D MOL

3D MOL
Formula
C34H52N18O2
Canonical SMILES
C(=N)(N/N=C(/c1cc(/C(=N/NC(=N)N)/C)cc(NC(=O)CCCCCCCCC(=<br />O)Nc2cc(cc(/C(=N/NC(=N)N)/C)c2)/C(=N/NC(=N)N)/C)c1)\C)N
CAS Number
CAS 352513-83-8
PubChem Compound ID
5745214
Target and Pathway
Target(s) Proto-oncogene c-RAF Target Info Modulator [527676]
References
Ref 521518ClinicalTrials.gov (NCT00038766) CNI-1493 for Treatment of Moderate to Severe Crohn's Disease. U.S. National Institutes of Health.
Ref 527676Specific inhibition of c-Raf activity by semapimod induces clinical remission in severe Crohn's disease. J Immunol. 2005 Aug 15;175(4):2293-300.

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