Drug Information

Drug General Information
Drug ID
D02CKX
Former ID
DAP000762
Drug Name
Carbimazole
Synonyms
Athyromazole; Atirozidina; Basolest; Carbethoxymethimazole; Carbimazol; Carbimazolum; Carbinazole; Carbotiroid; Mertiran; Neomercazole; TYRAZOL; Thyrostat; Carbimazol henning; Carbimazol spofa; CG1; Cg 1; Carbimazol henning (TN); Carbimazole (INN); Carbimazolum [INN-Latin]; Neo-Mercazole; Neo-Thyreostat; Neo-Tireol; Carbimazol [INN-Spanish, French]; Carbimazole [INN:BAN:DCF]; Ethyl 3-methyl-2-sulfanylideneimidazole-1-carboxylate; Ethyl 3-methyl-2-thioimidazoline-1-carboxylate; Ethyl 3-methyl-2-thioxo-2,3-dihydro-1H-imidazole-1-carboxylate; 1-Ethoxycarbonyl-3-methyl-2-thioimidazol; 1-Ethoxycarbonyl-3-methyl-2-thioxo-4-imidazoline; 1H-Imidazole-1-carboxylic acid, 2,3-dihydro-3-methyl-2-thioxo, ethyl ester; 1H-Imidazole-1-carboxylic acid, 2,3-dihydro-3-methyl-2-thioxo-, ethyl ester; 3-Methyl-2-thioxo-4-imidazoline-1-carboxylic acid ethyl ester; 4-Imidazoline-1-carboxylic acid, 3-methyl-2-thioxo-, ethyl ester
Drug Type
Small molecular drug
Indication Hyperthyroidism [ICD9: 242; ICD10:E05] Approved [550736]
Therapeutic Class
Antithyroid Agents
Structure
Download
2D MOL

3D MOL
Formula
C7H10N2O2S
Canonical SMILES
CCOC(=O)N1C=CN(C1=S)C
InChI
1S/C7H10N2O2S/c1-3-11-7(10)9-5-4-8(2)6(9)12/h4-5H,3H2,1-2H3
InChIKey
CFOYWRHIYXMDOT-UHFFFAOYSA-N
CAS Number
CAS 22232-54-8
PubChem Compound ID
31072
PubChem Substance ID
9817, 5179931, 7978859, 8171927, 10321736, 10514044, 11112670, 11373014, 11466467, 11467587, 11484918, 11486133, 11489067, 11491783, 12016059, 15017436, 26612901, 26679438, 26749040, 26749041, 34673253, 46506359, 47499680, 47795165, 47943908, 48019049, 48094653, 48415696, 49698494, 49980624, 50122572, 50122573, 50284853, 51091925, 56313590, 57311057, 85174590, 85788865, 87351869, 87566113, 92124636, 92125424, 92709756, 103649168, 103914223, 104119254, 104309910, 106194732, 117402917, 118307397
SuperDrug ATC ID
H03BB01
SuperDrug CAS ID
cas=022232548
Target and Pathway
Target(s) Thyroid peroxidase Target Info Inhibitor [537899]
BioCyc Pathway Thyroid hormone biosynthesis
KEGG Pathway Tyrosine metabolism
Metabolic pathways
Thyroid hormone synthesis
Autoimmune thyroid disease
NetPath Pathway TSH Signaling Pathway
PathWhiz Pathway Thyroid hormone synthesis
Reactome Thyroxine biosynthesis
WikiPathways Hematopoietic Stem Cell Differentiation
Differentiation Pathway
Metabolism of amino acids and derivatives
Thyroxine (Thyroid Hormone) Production
References
Ref 550736Drug information of Carbimazole, 2008. eduDrugs.
Ref 537899Diagnosis and treatment of thyrotoxicosis in childhood. A European questionnaire study. Eur J Endocrinol. 1994 Nov;131(5):467-73.

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