Drug Information

Drug General Information
Drug ID
D03BAC
Former ID
DIB014030
Drug Name
Revacept
Synonyms
Arterial thrombosis treatment, Trigen; PR-15; Antiplatelet protein therapy (arterial thrombosis/atherosclerosis), Trigen
Indication Arteriosclerosis [ICD9: 440; ICD10:I70] Phase 2 [523982]
Company
ProCorde GmbH
Target and Pathway
Target(s) Platelet glycoprotein VI Target Info Inhibitor [531438]
KEGG Pathway ECM-receptor interaction
Platelet activation
Reactome GPVI-mediated activation cascade
Cell surface interactions at the vascular wall
Platelet Adhesion to exposed collagen
WikiPathways Platelet Adhesion to exposed collagen
GPVI-mediated activation cascade
Cell surface interactions at the vascular wall
References
Ref 523982ClinicalTrials.gov (NCT01645306) Revacept in Symptomatic Carotid Stenosis (Revacept/CS/02). U.S. National Institutes of Health.
Ref 531438Novel antiplatelet drug revacept (Dimeric Glycoprotein VI-Fc) specifically and efficiently inhibited collagen-induced platelet aggregation without affecting general hemostasis in humans. Circulation.2011 May 3;123(17):1891-9.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.