Drug General Information
Drug ID
D03DJT
Former ID
DIB013439
Drug Name
Bococizumab
Drug Type
Antibody
Indication Chronic obstructive pulmonary disease [ICD9: 490-492, 494-496; ICD10:J40-J44, J47] Phase 3 [525217], [542700]
Company
Pfizer
Target and Pathway
Target(s) Proprotein convertase subtilisin/kexin type 9 Target Info [532996]
WikiPathways PCSK9-mediated LDLR degradation
References
Ref 525217ClinicalTrials.gov (NCT02458287) Efficacy, Safety, Tolerability And Actual Use Study Of Bococizumab And An Autoinjector (Pre-Filled Pen) In Subjects With Hyperlipidemia Or Dyslipidemia.
Ref 542700(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7730).
Ref 532996The dyslipidaemia market. Nat Rev Drug Discov. 2014 Nov;13(11):807-8.

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