Drug Information

Drug General Information
Drug ID
D03KVW
Former ID
DIB004268
Drug Name
MDX-1411
Drug Type
Antibody
Indication Cancer [ICD9: 140-229; ICD10:C00-C96] Phase 1 [522399]
Company
Medarex Inc
Target and Pathway
Target(s) CD70 Target Info [530370]
KEGG Pathway Cytokine-cytokine receptor interaction
NetPath Pathway IL2 Signaling Pathway
TNFalpha Signaling Pathway
RANKL Signaling Pathway
Reactome TNFs bind their physiological receptors
References
Ref 522399ClinicalTrials.gov (NCT00730652) Study of MDX-1411 in Patients With Relapsed/Refractory Chronic Lymphocytic Leukemia or Mantle Cell Lymphoma. U.S. National Institutes of Health.
Ref 530370Bristol-Myers Squibb swallows last of antibody pioneers. Nat Biotechnol. 2009 Sep;27(9):781-3.

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