Drug Information

Drug General Information
Drug ID
D03NZM
Former ID
DIB001599
Drug Name
T-588
Synonyms
(-)-(R)-1-(Benzothiophen-5-yl)-2-[2-(diethylamino)ethoxy]ethanol hydrochloride; 131965-06-5
Drug Type
Small molecular drug
Indication Amyotrophic lateral sclerosis [ICD9: 335.2; ICD10:G12.2] Discontinued in Phase 2 [545062]
Structure
Download
2D MOL

3D MOL
Formula
C16H24ClNO2S
Canonical SMILES
CCN(CC)CCOCC(C1=CC2=C(C=C1)SC=C2)O.Cl
InChI
1S/C16H23NO2S.ClH/c1-3-17(4-2)8-9-19-12-15(18)13-5-6-16-14(11-13)7-10-20-16;/h5-7,10-11,15,18H,3-4,8-9,12H2,1-2H3;1H/t15-;/m0./s1
InChIKey
BKMCUGFGPQNYHG-RSAXXLAASA-N
CAS Number
CAS 131965-06-5
PubChem Compound ID
132522
PubChem Substance ID
10243139, 12014796, 14753147, 14875192, 29310650, 49891165, 77362082, 104377647, 135089049, 226415642, 241035327
Target and Pathway
Target(s) Vesicular acetylcholine transporter Target Info Modulator [525943]
References
Ref 545062Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002000)
Ref 525943Involvement of noradrenaline transporters in S-nitrosocysteine-stimulated noradrenaline release from rat brain slices: existence of functional Na(+)-independent transporter activity. Neurochem Int. 2001 Apr;38(4):323-31.

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