Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D03SJA
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| Former ID |
DCL000518
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| Drug Name |
Dulanermin
|
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| Drug Type |
Small molecular drug
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| Indication | Indolent relapsed non-hodgkin's lymphoma; Metastatic non-small cell lung cancer; Metastatic colorectal cancer [ICD9: 140-229, 162, 200, 202, 202.8, 204.0, 153, 154; ICD10:C33, C33-C34, C34, C81-C86, C82-C85, C91.0, C18-C21] | Terminated | [550794] | ||
| Company |
Genentech
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| Structure |
|
Download2D MOL |
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| Formula |
C13H12N2O5S
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| Canonical SMILES |
CS(=O)(=O)NC1=C(C=C(C=C1)[N+](=O)[O-])OC2=CC=CC=C2
|
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| InChI |
1S/C13H12N2O5S/c1-21(18,19)14-12-8-7-10(15(16)17)9-13(12)20-11-5-3-2-4-6-11/h2-9,14H,1H3
|
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| InChIKey |
HYWYRSMBCFDLJT-UHFFFAOYSA-N
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| PubChem Compound ID | |||||
| PubChem Substance ID |
855635, 5912186, 6436673, 7404099, 7848112, 7889413, 7980127, 8149946, 8152768, 10321585, 11111520, 11111521, 11121727, 11122207, 11335868, 11361107, 11362857, 11364471, 11365419, 11367033, 11367981, 11369595, 11370925, 11370926, 11372711, 11373582, 11373834, 11376143, 11377757, 11462079, 11466222, 11467342, 11485118, 11485804, 11489357, 11491391, 11491993, 11495391, 12012650, 14752054, 17405416, 24277576, 24278583, 26612437, 26680139, 26697157, 26746940, 26746941, 26751468, 29215000
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| Target and Pathway | |||||
| Target(s) | TNF related apoptosis inducing ligand | Target Info | Modulator | [556264] | |
| PANTHER Pathway | Apoptosis signaling pathway | ||||
| Pathway Interaction Database | TRAIL signaling pathway | ||||
| Caspase Cascade in Apoptosis | |||||
| References | |||||
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