Drug General Information
Drug ID	D04TJP
Former ID	DCL000659
Drug Name	Totrombopag
Drug Type	Small molecular drug
Indication	Thrombocytopenia [ICD9: 287.3, 287.4, 287.5; ICD10:D69.6, P61.0]		Discontinued in Phase 1	[536737]
Company	GSK
Structure		Download 2D MOL 3D MOL
Formula	C25H21N8O2-
CAS Number	CAS 851606-62-7
PubChem Compound ID	71300872
Target and Pathway
Target(s)	Thrombopoietin Receptor	Target Info	Agonist	[550963]
KEGG Pathway	Cytokine-cytokine receptor interaction
	Jak-STAT signaling pathway
WikiPathways	Platelet Aggregation (Plug Formation)
References
Ref 536737	Emerging drugs for idiopathic thrombocytopenic purpura in adults. Expert Opin Emerg Drugs. 2008 Jun;13(2):237-54.
Ref 550963	Clinical pipeline report, company report or official report of GlaxoSmithKline (2009).

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