Drug Information

Drug General Information
Drug ID
D05EBY
Former ID
DIB008329
Drug Name
PCSK9 Adnectin
Synonyms
PCSK9 Adnectin (cardiovascular); Adnectin program (cardiovascular disease), Adnexus/BMS; PCSK9 Adnectin (cardiovascular), Bristol-Myers Squibb
Indication Cardiovascular disorder [ICD10:I00-I99] Phase 1 [525391]
Company
Bristol-myers squibb
Target and Pathway
Target(s) Proprotein convertase subtilisin/kexin type 9 Target Info Modulator [532837]
WikiPathways PCSK9-mediated LDLR degradation
References
Ref 525391Cholesterol-lowering blockbuster candidates speed into Phase III trials. Nat Rev Drug Discov. 2012 Nov;11(11):817-9. doi: 10.1038/nrd3879.
Ref 532837Pharmacologic profile of the Adnectin BMS-962476, a small protein biologic alternative to PCSK9 antibodies for low-density lipoprotein lowering. J Pharmacol Exp Ther. 2014 Aug;350(2):412-24.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.