Drug Information

Drug General Information
Drug ID
D05FBZ
Former ID
DIB015155
Drug Name
CPHPC
Synonyms
Amyloid beta inhibitor; SAP binding inhibitor, Roche; Serum amyloid P binding inhibitor, Roche; Ro-63-8695
Drug Type
Small molecular drug
Indication Parkinson's disease [ICD9: 332; ICD10:G20] Phase 1/2 [525166], [543014]
Company
F Hoffmann-La Roche Ltd
Structure
Download
2D MOL

3D MOL
Formula
C16H24N2O6
InChI
InChI=1S/C16H24N2O6/c19-13(17-9-3-5-11(17)15(21)22)7-1-2-8-14(20)18-10-4-6-12(18)16(23)24/h11-12H,1-10H2,(H,21,22)(H,23,24)/t11-,12-/m1/s1
InChIKey
HZLAWYIBLZNRFZ-VXGBXAGGSA-N
CAS Number
CAS 224624-80-0
PubChem Compound ID
125516
PubChem Substance ID
10241357, 14827162, 14900283, 29305302, 50075682, 57341393, 79025614, 99431563, 103194049, 104361529, 128135310, 135081826, 142730144, 162221063, 163614779, 163614781, 198964792, 223811111, 227737743, 249565936
Target and Pathway
Target(s) Serum amyloid P-component Target Info Modulator
Reactome Amyloid formation
WikiPathways Human Complement System
Amyloids
References
Ref 525166ClinicalTrials.gov (NCT02425241) Depletion of Serum Amyloid P Component to Enhance the Immune Response to DNA Vaccination. U.S. National Institutes of Health.
Ref 543014(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8256).

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