Drug Information

Drug General Information
Drug ID
D05MAT
Former ID
DNC007621
Drug Name
1-adamantan-1-yl-3-(3-hydroxypropyl)urea
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529063]
Structure
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2D MOL

3D MOL
Formula
C14H24N2O2
Canonical SMILES
C1C2CC3CC1CC(C2)(C3)NC(=O)NCCCO
InChI
1S/C14H24N2O2/c17-3-1-2-15-13(18)16-14-7-10-4-11(8-14)6-12(5-10)9-14/h10-12,17H,1-9H2,(H2,15,16,18)
InChIKey
QADGUCFKHPQVSD-UHFFFAOYSA-N
PubChem Compound ID
2235217
Target and Pathway
Target(s) Soluble epoxide hydrolase Target Info Inhibitor [529063]
KEGG Pathway Arachidonic acid metabolism
Metabolic pathways
Peroxisome
PathWhiz Pathway Arachidonic Acid Metabolism
WikiPathways Metapathway biotransformation
Arachidonate Epoxygenase / Epoxide Hydrolase
Arachidonic acid metabolism
References
Ref 529063J Med Chem. 2007 Oct 18;50(21):5217-26. Epub 2007 Sep 26.1,3-disubstituted ureas functionalized with ether groups are potent inhibitors of the soluble epoxide hydrolase with improved pharmacokineticproperties.
Ref 529063J Med Chem. 2007 Oct 18;50(21):5217-26. Epub 2007 Sep 26.1,3-disubstituted ureas functionalized with ether groups are potent inhibitors of the soluble epoxide hydrolase with improved pharmacokineticproperties.

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