Drug Information

Drug General Information
Drug ID
D06FHQ
Former ID
DNCL002307
Drug Name
BMS-936561
Indication Hematological malignancies [ICD9: 200-209; ICD10:C81-C86] Phase 1 [549690]
Company
Bristol-Myers Squibb
Target and Pathway
Target(s) CD70 Target Info Modulator [533210]
KEGG Pathway Cytokine-cytokine receptor interaction
NetPath Pathway IL2 Signaling Pathway
TNFalpha Signaling Pathway
RANKL Signaling Pathway
Reactome TNFs bind their physiological receptors
References
Ref 549690J Clin Oncol 32:5s, 2014 (suppl, abstr 2558).
Ref 533210Pharmacokinetic characterization of BMS-936561, an anti-CD70 antibody-drug conjugate, in preclinical animal species and prediction of its pharmacokinetics in humans. Biopharm Drug Dispos. 2015 Apr 13.

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