Drug Information

Drug General Information
Drug ID
D06YYD
Former ID
DAP001443
Drug Name
Dexlansoprazole
Synonyms
Kapidex; T 168390; TAK 390; KS-1075; Dexlansoprazole (INN/USAN)
Drug Type
Small molecular drug
Indication Erosive esophagitis; Non-erosive gastro-esophageal reflux disease [ICD9: 530; ICD10:K20, K21] Approved [538589]
Company
Takeda
Structure
Download
2D MOL

3D MOL
Formula
C16H14F3N3O2S
Canonical SMILES
CC1=C(C=CN=C1CS(=O)C2=NC3=CC=CC=C3N2)OCC(F)(F)F
InChI
1S/C16H14F3N3O2S/c1-10-13(20-7-6-14(10)24-9-16(17,18)19)8-25(23)15-21-11-4-2-3-5-12(11)22-15/h2-7H,8-9H2,1H3,(H,21,22)/t25-/m1/s1
InChIKey
MJIHNNLFOKEZEW-RUZDIDTESA-N
CAS Number
CAS 103577-45-3
PubChem Compound ID
9578005
PubChem Substance ID
14901842, 15375021, 23998121, 25819922, 44715913, 80665304, 89736101, 96025586, 104179070, 104234371, 126682042, 128604168, 135156589, 137931058, 140767605, 162189572, 164178109, 164761527, 170503333, 175265917, 175269426, 175611039, 178102134, 184527042, 185965235, 210274918, 210280553, 223658647, 223798807, 226429139, 241033947, 251879797, 252151427, 252431524, 252811271
ChEBI ID
ChEBI:6375
SuperDrug ATC ID
A02BC06
Target and Pathway
Target(s) Potassium-transporting ATPase alpha chain 1 Target Info Inhibitor [551717]
KEGG Pathway Oxidative phosphorylation
Collecting duct acid secretion
Gastric acid secretion
PathWhiz Pathway Gastric Acid Production
Reactome Ion transport by P-type ATPases
WikiPathways Iron uptake and transport
Secretion of Hydrochloric Acid in Parietal Cells
References
Ref 538589FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 022287.
Ref 551717Clinical pipeline report, company report or official report of Takeda (2009).

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