Drug Information

Drug General Information
Drug ID
D07DSN
Former ID
DIB014767
Drug Name
BIIB-033
Drug Type
Antibody
Indication Multiple scierosis [ICD9: 340; ICD10:G35] Phase 2 [533001]
Target and Pathway
Target(s) Leucine-rich repeat neuronal protein 1 Target Info [533001]
Reactome Axonal growth inhibition (RHOA activation)
WikiPathways BDNF signaling pathway
Signalling by NGF
References
Ref 533001Randomized phase I trials of the safety/tolerability of anti-LINGO-1 monoclonal antibody BIIB033. Neurol Neuroimmunol Neuroinflamm. 2014 Aug 21;1(2):e18.
Ref 533001Randomized phase I trials of the safety/tolerability of anti-LINGO-1 monoclonal antibody BIIB033. Neurol Neuroimmunol Neuroinflamm. 2014 Aug 21;1(2):e18.

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