Drug Information

Drug General Information
Drug ID
D07JRL
Former ID
DIB006933
Drug Name
Epithalon
Synonyms
Epitalon; BDM-E; Epitalon (Russian Academy of Medical Sciences); Retinal disease therapeutic, Biodiem; L-Alanyl-L-glutamyl-L-aspartyl-glycine
Drug Type
Small molecular drug
Indication Ocular inflammation [ICD9: 370.33; ICD10:H16.229] Phase 1/2 [548016]
Company
BioDiem Ltd
Structure
Download
2D MOL

3D MOL
Formula
C14H22N4O9
Canonical SMILES
CC(C(=O)NC(CCC(=O)O)C(=O)NC(CC(=O)O)C(=O)NCC(=O)O)N
InChI
1S/C14H22N4O9/c1-6(15)12(25)17-7(2-3-9(19)20)14(27)18-8(4-10(21)22)13(26)16-5-11(23)24/h6-8H,2-5,15H2,1H3,(H,16,26)(H,17,25)(H,18,27)(H,19,20)(H,21,22)(H,23,24)/t6-,7-,8-/m0/s1
InChIKey
HGHOBRRUMWJWCU-FXQIFTODSA-N
CAS Number
CAS 307297-39-8
PubChem Compound ID
219042
PubChem Substance ID
9374247, 14780695, 14829908, 30422416, 49973292, 52539628, 57399833, 103827176, 113468464, 117538801, 128056784, 135141173, 198944217, 231485478, 252450010
Target and Pathway
Target(s) Telomerase reverse transcriptase Target Info Modulator [526699]
NetPath Pathway IL2 Signaling Pathway
Pathway Interaction Database Validated targets of C-MYC transcriptional activation
Regulation of Telomerase
IL2 signaling events mediated by PI3K
Regulation of nuclear beta catenin signaling and target gene transcription
HIF-1-alpha transcription factor network
Reactome Formation of the beta-catenin:TCF transactivating complex
References
Ref 548016Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800021226)
Ref 526699Epithalon peptide induces telomerase activity and telomere elongation in human somatic cells. Bull Exp Biol Med. 2003 Jun;135(6):590-2.

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