Drug General Information
Drug ID
D07LBQ
Former ID
DIB002845
Drug Name
GSK2398852
Synonyms
2398852
Drug Type
Antibody
Indication Amyloidosis [ICD9: 277.3; ICD10:E85] Phase 1 [524198], [543013]
Target and Pathway
Target(s) Serum amyloid P-component Target Info [524198], [531012]
Reactome Amyloid formation
WikiPathways Human Complement System
Amyloids
References
Ref 524198ClinicalTrials.gov (NCT01777243) A Study to Evaluate the Safety of GSK2398852 When Co-administered With GSK2315698 in Patients With Systemic Amyloidosis. U.S. National Institutes of Health.
Ref 543013(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8255).
Ref 524198ClinicalTrials.gov (NCT01777243) A Study to Evaluate the Safety of GSK2398852 When Co-administered With GSK2315698 in Patients With Systemic Amyloidosis. U.S. National Institutes of Health.
Ref 531012PRM-151 (recombinant human serum amyloid P/pentraxin 2) for the treatment of fibrosis. Drug News Perspect. 2010 Jun;23(5):305-15.

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