Drug General Information
Drug ID	D07QGX
Former ID	DNC012956
Drug Name	2-amino-2-(2,4-difluorophenyl)acetic acid
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[527946]
Structure		Download 2D MOL 3D MOL
Formula	C8H7F2NO2
Canonical SMILES	C1=CC(=C(C=C1F)F)C(C(=O)O)N
InChI	1S/C8H7F2NO2/c9-4-1-2-5(6(10)3-4)7(11)8(12)13/h1-3,7H,11H2,(H,12,13)
InChIKey	COIWYFIMAXMSKX-UHFFFAOYSA-N
PubChem Compound ID	2737050
Target and Pathway
Target(s)	Voltage-dependent calcium channel subunit alpha-2/delta-1	Target Info	Inhibitor	[527946]
KEGG Pathway	MAPK signaling pathway
	Cardiac muscle contraction
	Adrenergic signaling in cardiomyocytes
	Oxytocin signaling pathway
	Hypertrophic cardiomyopathy (HCM)
	Arrhythmogenic right ventricular cardiomyopathy (ARVC)
	Dilated cardiomyopathy
PANTHER Pathway	Muscarinic acetylcholine receptor 2 and 4 signaling pathway
WikiPathways	Arrhythmogenic Right Ventricular Cardiomyopathy
	miR-targeted genes in muscle cell - TarBase
	miR-targeted genes in lymphocytes - TarBase
References
Ref 527946	Bioorg Med Chem Lett. 2006 Mar 1;16(5):1138-41. Epub 2005 Dec 27.Structure-activity relationships of alpha-amino acid ligands for the alpha2delta subunit of voltage-gated calcium channels.
Ref 527946	Bioorg Med Chem Lett. 2006 Mar 1;16(5):1138-41. Epub 2005 Dec 27.Structure-activity relationships of alpha-amino acid ligands for the alpha2delta subunit of voltage-gated calcium channels.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.