Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D07VFD
|
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| Former ID |
DIB007873
|
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| Drug Name |
Mirogabalin
|
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| Drug Type |
Small molecular drug
|
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| Structure |
|
Download2D MOL |
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| Formula |
C12H19NO2
|
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| InChI |
InChI=1S/C12H19NO2/c1-2-8-3-9-5-12(7-13,6-11(14)15)10(9)4-8/h4,9-10H,2-3,5-7,13H2,1H3,(H,14,15)/t9-,10-,12-/m1/s1
|
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| InChIKey |
FTBQORVNHOIASH-CKYFFXLPSA-N
|
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Voltage-dependent calcium channel subunit alpha-2/delta-1 | Target Info | Modulator | [528162], [532966] | |
| PANTHER Pathway | Muscarinic acetylcholine receptor 2 and 4 signaling pathway | ||||
| References | |||||
| Ref 543055 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8303). | ||||
| Ref 549169 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800033181) | ||||
| Ref 528162 | Pregabalin reduces the release of synaptic vesicles from cultured hippocampal neurons. Mol Pharmacol. 2006 Aug;70(2):467-76. Epub 2006 Apr 26. | ||||
| Ref 532966 | Efficacy and safety of mirogabalin (DS-5565) for the treatment of diabetic peripheral neuropathic pain: a randomized, double-blind, placebo- and active comparator-controlled, adaptive proof-of-concept phase 2 study. Diabetes Care. 2014 Dec;37(12):3253-61. | ||||
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