Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D08KSU
|
||||
| Former ID |
DCL001058
|
||||
| Drug Name |
AP12009
|
||||
| Drug Type |
Antisense drug
|
||||
| Indication | Colorectal cancer [ICD9: 153, 154; ICD10:C18-C21] | Phase 3 | [522449] | ||
| Therapeutic Class |
Antisense
|
||||
| Company |
Antisense therapeutics
|
||||
| Target and Pathway | |||||
| Target(s) | Transforming growth factor beta 2 | Target Info | [551023] | ||
| KEGG Pathway | MAPK signaling pathway | ||||
| Cytokine-cytokine receptor interaction | |||||
| FoxO signaling pathway | |||||
| Cell cycle | |||||
| Endocytosis | |||||
| TGF-beta signaling pathway | |||||
| Osteoclast differentiation | |||||
| Hippo signaling pathway | |||||
| Leishmaniasis | |||||
| Chagas disease (American trypanosomiasis) | |||||
| Malaria | |||||
| Toxoplasmosis | |||||
| Amoebiasis | |||||
| Tuberculosis | |||||
| Hepatitis B | |||||
| HTLV-I infection | |||||
| Pathways in cancer | |||||
| Proteoglycans in cancer | |||||
| MicroRNAs in cancer | |||||
| Colorectal cancer | |||||
| Renal cell carcinoma | |||||
| Pancreatic cancer | |||||
| Chronic myeloid leukemia | |||||
| Inflammatory bowel disease (IBD) | |||||
| Rheumatoid arthritis | |||||
| Hypertrophic cardiomyopathy (HCM) | |||||
| Dilated cardiomyopathy | |||||
| PANTHER Pathway | TGF-beta signaling pathway | ||||
| References | |||||
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