Drug Information

Drug General Information
Drug ID
D09INF
Former ID
DCL000860
Drug Name
Laquinamod
Drug Type
Small molecular drug
Indication Multiple scierosis [ICD9: 340; ICD10:G35] Phase 3 [536604]
Company
Active Biotech; Teva
Structure
Download
2D MOL

3D MOL
Formula
C19H16ClN2NaO3
Canonical SMILES
CCN(C1=CC=CC=C1)C(=O)C2=C(C3=C(C=CC=C3Cl)N(C2=O)C)[O-].<br />[Na+]
InChI
1S/C19H17ClN2O3.Na/c1-3-22(12-8-5-4-6-9-12)19(25)16-17(23)15-13(20)10-7-11-14(15)21(2)18(16)24;/h4-11,23H,3H2,1-2H3;/q;+1/p-1
InChIKey
JWHPPWBIIQMBQC-UHFFFAOYSA-M
CAS Number
CAS 248282-07-7
PubChem Compound ID
23697158
PubChem Substance ID
12015373, 16684127, 56048795, 96025621, 134339321, 135203220, 160681713, 164043544, 164228134, 198970851, 224362604, 228149892
Target and Pathway
Target(s) Macrophage inflammatory protein-2-alpha Target Info Modulator [536604]
KEGG Pathway Cytokine-cytokine receptor interaction
Chemokine signaling pathway
NF-kappa B signaling pathway
NOD-like receptor signaling pathway
TNF signaling pathway
Salmonella infection
Legionellosis
NetPath Pathway IL-7 Signaling Pathway
IL1 Signaling Pathway
IL4 Signaling Pathway
TNFalpha Signaling Pathway
IL5 Signaling Pathway
PANTHER Pathway CCKR signaling map ST
Reactome Chemokine receptors bind chemokines
G alpha (i) signalling events
WikiPathways Cytokines and Inflammatory Response
Spinal Cord Injury
GPCR ligand binding
GPCR downstream signaling
References
Ref 536604Multiple sclerosis: current and future treatment options. Endocr Metab Immune Disord Drug Targets. 2007 Dec;7(4):292-9.
Ref 536604Multiple sclerosis: current and future treatment options. Endocr Metab Immune Disord Drug Targets. 2007 Dec;7(4):292-9.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.