Drug General Information
Drug ID	D09UXA
Former ID	DNC014878
Drug Name	Trans-dimethyl gababutin
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[530573]
Structure		Download 2D MOL 3D MOL
Formula	C10H19NO2
Canonical SMILES	CC1CC(CC1C)(CC(=O)O)CN
InChI	1S/C10H19NO2/c1-7-3-10(6-11,4-8(7)2)5-9(12)13/h7-8H,3-6,11H2,1-2H3,(H,12,13)/t7-,8-/m0/s1
InChIKey	IUVMAUQEZFTTFB-YUMQZZPRSA-N
PubChem Compound ID	9794485
Target and Pathway
Target(s)	Voltage-dependent calcium channel subunit alpha-2/delta-1	Target Info	Inhibitor	[530573]
KEGG Pathway	MAPK signaling pathway
	Cardiac muscle contraction
	Adrenergic signaling in cardiomyocytes
	Oxytocin signaling pathway
	Hypertrophic cardiomyopathy (HCM)
	Arrhythmogenic right ventricular cardiomyopathy (ARVC)
	Dilated cardiomyopathy
PANTHER Pathway	Muscarinic acetylcholine receptor 2 and 4 signaling pathway
WikiPathways	Arrhythmogenic Right Ventricular Cardiomyopathy
	miR-targeted genes in muscle cell - TarBase
	miR-targeted genes in lymphocytes - TarBase
References
Ref 530573	Bioorg Med Chem Lett. 2010 Jan 15;20(2):461-4. Epub 2009 Nov 27.Synthesis and in vivo evaluation of bicyclic gababutins.
Ref 530573	Bioorg Med Chem Lett. 2010 Jan 15;20(2):461-4. Epub 2009 Nov 27.Synthesis and in vivo evaluation of bicyclic gababutins.

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