Drug General Information
Drug ID	D09WOY
Former ID	DIB003946
Drug Name	SB-559457
Indication	Acute myeloid leukemia [ICD9: 205; ICD10:C92.0]		Investigative	[543468]
Company	GlaxoSmithKline plc
Structure		Download 2D MOL 3D MOL
Canonical SMILES	N(=C\1/C(=O)N(N=C1C)c1ccc(c(c1)C)C)\Nc1cc(cc(c1O)c1cc(c<br />cc1)C(=O)O)F
Target and Pathway
Target(s)	Thrombopoietin Receptor	Target Info	Agonist	[543468]
KEGG Pathway	Cytokine-cytokine receptor interaction
	Jak-STAT signaling pathway
WikiPathways	Platelet Aggregation (Plug Formation)
References
Ref 543468	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1722).
Ref 543468	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1722).

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