Drug General Information
Drug ID
D0CT4D
Former ID
DCL000730
Drug Name
Brivaracetam
Synonyms
Rikelta; UCB-34714; Brivaracetam (USAN/INN)
Drug Type
Small molecular drug
Indication Partial-onset seizures [ICD10:G00-G99] Approved [889440]
Pain; Epilepsy [ICD9: 338, 356.0, 356.8, 780; ICD10:G64, G90.0, R52, G89, G40] Phase 3 [536757], [536934]
Company
UCB
Structure
Download
2D MOL

3D MOL

Formula
C11H20N2O2
Canonical SMILES
CCCC1CC(=O)N(C1)C(CC)C(=O)N
InChI
1S/C11H20N2O2/c1-3-5-8-6-10(14)13(7-8)9(4-2)11(12)15/h8-9H,3-7H2,1-2H3,(H2,12,15)/t8-,9+/m1/s1
InChIKey
MSYKRHVOOPPJKU-BDAKNGLRSA-N
CAS Number
CAS 357336-20-0
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) Synaptic vesicle glycoprotein 2A Target Info Inhibitor [536234], [536845]
KEGG Pathway ECM-receptor interaction
References
Ref 536757New molecular targets for antiepileptic drugs: alpha(2)delta, SV2A, and K(v)7/KCNQ/M potassium channels. Curr Neurol Neurosci Rep. 2008 Jul;8(4):345-52.
Ref 536934Progress report on new antiepileptic drugs: a summary of the Ninth Eilat Conference (EILAT IX). Epilepsy Res. 2009 Jan;83(1):1-43. Epub 2008 Nov 12.
Ref 8894402016 FDA drug approvals. Nat Rev Drug Discov. 2017 Feb 2;16(2):73-76. doi: 10.1038/nrd.2017.14.
Ref 536234New antiepileptic drugs that are second generation to existing antiepileptic drugs. Expert Opin Investig Drugs. 2006 Jun;15(6):637-47.
Ref 536845Pharmacological management of epilepsy: recent advances and future prospects. Drugs. 2008;68(14):1925-39.

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